Gene Expression Profiles of Sporadic Canine Hemangiosarcoma Are Uniquely Associated with Breed
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منابع مشابه
Gene Expression Profiles of Sporadic Canine Hemangiosarcoma Are Uniquely Associated with Breed
The role an individual's genetic background plays on phenotype and biological behavior of sporadic tumors remains incompletely understood. We showed previously that lymphomas from Golden Retrievers harbor defined, recurrent chromosomal aberrations that occur less frequently in lymphomas from other dog breeds, suggesting spontaneous canine tumors provide suitable models to define how heritable t...
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Results IL-8 mRNA expression was variable among the tissue samples and both IL-8 mRNA and protein were variable among the cell lines. In contrast, IL-8 receptor mRNA and protein showed minimal variance. “IL-8 high” and “IL-8 low” groups were defined from the HSA tumor samples based on gene expression profiles. The “IL-8 high” group was associated with a “reactive microenvironment,” showing enri...
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BACKGROUND Angiosarcomas (AS) are rare in humans, but they are a deadly subtype of soft tissue sarcoma. Discovery sequencing in AS, especially the visceral form, is hampered by the rarity of cases. Most diagnostic material exists as archival formalin fixed, paraffin embedded tissue which serves as a poor source of high quality DNA for genome-wide sequencing. We approached this problem through c...
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6 Peakall R. & Smouse P.E. (2006)Mol Ecol Notes 6, 288–95. 7 Vignaud T. et al. (2013) PLoS ONE 8, e61067. 8 Lucentini L. et al. (2006) Fish Res 80, 251–62. 9 Van Oosterhout C. et al. (2004) Mol Ecol Notes 4, 535–8. 10 Chapuis M.P. & Estoup A. (2007)Mol Biol Evol 24, 621–31. 11 Kelly A.C. et al. (2011) Genet Mol Res 10, 2534–53. 12 Kalinowski S.T. & Taper M.L. (2006) Conserv Genet 7, 991–5. 13 C...
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Despite the increasing knowledge about the genetic alterations and molecular pathways involved in gliomas, few studies have investigated the association between the gene expression profiles (GEP) and both cytogenetics and histopathology of gliomas. Here, we analyzed the GEP (U133Plus2.0 chip) of 40 gliomas (35 astrocytic tumors, 3 oligodendrogliomas, and 2 mixed tumors) and their association wi...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0005549